BDBM50269847 CHEMBL4097025

SMILES CNC(=O)N1CCc2c(C1)c(nn2C1CCOCC1)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F

InChI Key InChIKey=CQCWHSDMJBAGDC-UHFFFAOYSA-N

Data  21 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269847   

TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from recombinant His-tagged TAF1 bromodomain-2 (unknown origin) measured after 10 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged TAF1 bromodomain-1 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed